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MPEG-SVA 甲氧基PEG琥珀酰亚胺戊酸酯

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  • 产品名称:MPEG-SVA 甲氧基PEG琥珀酰亚胺戊酸酯
  • 产品型号:PS1-H5
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简单介绍

MPEG-SVA 甲氧基PEG琥珀酰亚胺戊酸酯

产品描述
基本信息
   名:甲氧基聚乙二醇琥珀酰亚胺戊酸酯 MPEG-SVA纯度:>95%
分子式:SVA-(CH2CH2O)nOCH3分子量:3505507501000200050001000020000
产品属性:单官能团PEG   观:粘稠液体或者固体粉末,取决于分子量
保存条件:零下20℃   途:仅供科研实验使用,不用于诊治
溶解性:溶于大部分有机溶剂,如:DCM、DMF、DMSO、THF等等。在水中有很好的溶解性。
注意事项:取用一定要干燥,避免频繁的溶解和冻干。
应用简介:N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH2) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our  mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.
反应简介:Reaction Procedures:

Generally, a 10 to 50-fold molar excess of NHS PEG over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

Conjugation buffer: Sodium bicarbonate 100 mM buffer, pH 8.5 or other amine-free buffer at pH 7-8.5.
PEG NHS stock solution: 100 mg in 1 mL conjugation buffer.
Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:

Dissolve targeted materials in conjugation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add NHS PEG stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG NHS needed for optimal conjugation; Allow mixture agitates at room temperature for 30~60 min at room temperature or 2 hours at 4 0C. Conjugates can be purified either by size exclusion chromatography or dialysis.

结构式



质量控制
分    析:COANMRGPC
包装及价格
货号-规格价格(RMB预计发货时间
PS1-H5-1g现询3-5天
PS1-H5-5g现询3-5天
PS1-H5-10g现询3-5天
包装:1g 每瓶;5g 每瓶;10g 每瓶,大包装另寻
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PS1-CM2甲氧基PEG丙酸mPEG-PA95%3505507501000200050001000020000
PS1-AC甲氧基PEG丙烯酸酯mPEG-Acrylate,MPEG-DA95%3505507501000200050001000020000
PS1-MA甲氧基PEG甲基丙烯酸酯mPEG-MeAc,MPEG-MA95%3505507501000200050001000020000
PS1-ACA甲氧基PEG丙烯酰胺mPEG-ACA95%3505507501000200050001000020000
PS1-M甲氧基PEG马来酰亚胺mPEG-MAL95%3505507501000200050001000020000
PS1-DE甲氧基PEG-N-二硬脂酰磷脂酰乙酰胺mPEG-DSPE95%3505507501000200050001000020000
PS1-H甲氧基PEG活性酯Succinimidyl PEG NHS, mPEG-NHS95%3505507501000200050001000020000
PS1-SSH甲氧基PEG二巯基-活性酯Methoxy PEG dithiol NHS95%3505507501000200050001000020000
PS1-H1甲氧基PEG-N羟基琥珀酰亚胺酯mPEG-SCM95%3505507501000200050001000020000
PS1-H5甲氧基PEG琥珀酰亚胺戊酸酯MPEG-SVA95%3505507501000200050001000020000
PS1-H4甲氧基-PEG戊二酸琥珀酰酯mPEG-SG95%3505507501000200050001000020000
PS1-HA4甲氧基-PEG戊二酸酰胺琥珀酰酯mPEG-GAS95%3505507501000200050001000020000
PS1-HA3甲氧基-PEG丁二酸酰胺琥珀酰酯mPEG-SAS95%3505507501000200050001000020000
PS1-H3甲氧基-PEG丁二酸琥珀酰酯mPEG-SS95%3505507501000200050001000020000
PS1-H2甲氧基-PEG-N琥珀酰亚胺丙酸酯mPEG-SPA95%3505507501000200050001000020000
PS1-AZ甲氧基PEG叠氮mPEG-Azide95%3505507501000200050001000020000
PS1-BN甲氧基PEG生物素mPEG-Biotin95%3505507501000200050001000020000
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PS1-R甲氧基PEG罗丹明mPEG-Rhodamine,MPEG-RB95%3505507501000200050001000020000
PS1-MS甲氧基PEG甲磺酸酯mPEG-OMs95%3505507501000200050001000020000
PS1-TS甲氧基PEG对甲苯磺酸酯mPEG-OTs95%3505507501000200050001000020000
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