上海芃圣生物科技有限公司 主营:修饰性PEG,多臂,氨基PEG,巯基PEG,羟基PEG,羧基PEG,荧光素PEG,生物素PEG, 活性酯PEG……
所在位置:
产品详情

甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)

  • 如果您对该产品感兴趣的话,可以
  • 产品名称:甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)
  • 产品型号:PS1-DB
  • 产品展商:ponsure
  • 产品文档:无相关文档
简单介绍

甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO) mPEG DBCO, also called methoxy PEG DBCO, is a pegylated DBCO (dibenzocyclooctyne) derivative that can react with azide group without need any metal catalyst. 甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)

产品描述

甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)

甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)


名称

货号

英文名、缩写

分子量

规格

价格

MPEG-DBCO

PS1-DB-5K

MPEG-ADIBO, MPEG-DBCO

5000

0.1g0.5g

现询

MPEG-DBCO

PS1-DB-2K

MPEG-ADIBO, MPEG-DBCO

2000

0.1g0.5g

现询

MPEG-DBCO

PS1-DB-1K

MPEG-ADIBO, MPEG-DBCO

1000

0.1g0.5g

现询

MPEG-DBCO

PS1-DB-10K

MPEG-ADIBO, MPEG-DBCO

10000

0.1g0.5g

现询

MPEG-DBCO

PS1-DB-20K

MPEG-ADIBO, MPEG-DBCO

20000

0.1g0.5g

现询

MPEG-DBCO

PS1-DB-30K

MPEG-ADIBO, MPEG-DBCO

30000

0.1g0.5g

现询

(备注:非常规分子量:3505005507501k。精确聚合度的小分子定制。)

 

结构式:

==========================================================

 

  

基本信息:

========================================================== 

中文名称:甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)

别名:MPEG-ADIBO, MPEG-DBCO

英文名称:mPEG-DBCO ; mPEG-Dibenzocycolctyne

CAS:-

分子量:350、500、550、750、1K、2K、5K、10K、20K、30K

纯度:95%以上

 

应用简介:

========================================================== 

mPEG DBCO, also called methoxy PEG DBCO, is a pegylated DBCO (dibenzocyclooctyne) derivative that can react with azide group without need any metal catalyst. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free Click reaction, is a bioorthogaonal reaction that enables the conjugation of two molecules in aqueous solution. PEG DBCO derivatives have excellent water solubility, possess fast kinetics and stability in aqueous buffer. They are one of the best pegylation reagents to modify proteins, peptides, antibodies, biopolymers and particles via copper free Click Chemistry reaction.

 

Copper-free Click reaction procedures:

 

Prepare the azide-containing reagents in reaction buffer.

Add PEG DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.

Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C.

Purify conjugates either by dialysis or size-exclusion chromatograph.

 

 

物理性质:

========================================================== 

状态:淡黄色到白色固体,或者半固体,取决于分子量。

溶解性:溶于水,乙醇,DMSO等溶剂。

保持条件:-20℃长期保存,避光,干燥。

注意事项:取用一定要干燥,避免频繁的溶解和冻干。

反应性:DBCO于含有N3基团的反应。

 

技术指标:

========================================================== 

纯度(PEG):95%以上

取代率(DBCO):95%以上

分散系数(PDI):小于等于1.05

分析:COA、GPC、NMR、MALDI-TOF

 

甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)

甲氧基聚乙二醇-dibenzocyclooctyne (MPEG-DBCO)


产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
Copyright@ 2003-2018  上海芃圣生物科技有限公司版权所有      电话:400-001-3539 / 17717528790 传真: 地址:上海市浦东新区 邮编: